C:\Users\Administrator\virtualbox>vagrant up Bringing machine ‘default‘ up with ‘virtualbox‘ provider... There was an error while executing `VBoxManage`, a CLI used by Vagrant for controlling VirtualBox. The command and stderr is shown below. Command: ["list", "hostonlyifs"] Stderr: VBoxManage.exe: error: Failed to create the VirtualBox object! VBoxManage.exe: error: Code E_NOINTERFACE (0x80004002) - No such interface suppo rted (extended info not available) VBoxManage.exe: error: Most likely, the VirtualBox COM server is not running or failed to start.
根据网上说的VirtualBox兼容性问题，在VirtualBox安装目录中找到VBoxManage.exe，右击选择属性，设置Windows Server 2008兼容模式运行。再执行vagrant up，正常运行，问题解决。
原文：http://my.oschina.net/yearnfar/blog/493498