方法一：
Set wshell=CreateObject("WScript.Shell")
wshell.Run """C:\Program Files\360\360se\360se.exe""",5,True
Set wshell = Nothing
方法二：
temp="C:\Program Files\360\360se3\360se.exe"
path = Chr(34) & temp & Chr(34)
Set wshell=CreateObject("WScript.Shell")
wshell.Run path,1,True
Set wshell = Nothing
方法三：
Public Const vbQuote = """"
temp="C:\Program Files\360\360se3\360se.exe"
path = vbQuote & temp & vbQuote
Set wshell=CreateObject("WScript.Shell")
wshell.Run path,1,True
Set wshell = Nothing
原文：http://www.jb51.net/article/72721.htm