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Delivering highly accurate long reads to drive discovery in life science

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DELIVERING HIGHLY ACCURATE LONG READS TO DRIVE DISCOVERY IN LIFE SCIENCE

What is SMRT Sequencing?

Single Molecule, Real-Time (SMRT) Sequencing is the core technology powering our long-read sequencing platforms. This innovative approach was the first of its kind and is now a proven technology used in all fields of life science.

Learn how to go from DNA to discovery with SMRT Sequencing in this short video.

 

Original Publication: Eid, J., et al. (2009) Real-time DNA sequencing from single polymerase molecules. Science, 323(5910), 133–138.


 

 

What are the Advantages of SMRT Sequencing?

 

技术分享图片

Long Reads

 

With reads tens of kilobases in length you can readily assemble complete genomes and sequence full-length transcripts.

Explore the benefits of long reads


High Accuracy

 

Sequencing free of systematic error achieves >99.999% consensus accuracy.

Learn more about high accuracy


Uniform Coverage

 

No bias based on GC content means you can sequence through region inaccessible to other technologies.

Discover how uniform coverage lets you see more


Single-Molecule Resolution

 

Capturing sequence data from native DNA or RNA molecules enables highly accurate long reads with >99% single-molecule accuracy.

See the difference single-molecule resolution makes


Epigenetics

 

With no PCR amplification step, base modifications are directly detected during sequencing.

Get more from your sequencing with epigenetics


 

What Can You Do With SMRT Sequencing?

Explore the full range of SMRT Sequencing applications.

 

技术分享图片 Whole Genome Sequencing

 

For humans, plants, animals and microbes including de novo assembly and variant detection

技术分享图片 Complex Populations

 

Understand variants among bacterial, viral and cancer cell populations

 

技术分享图片 RNA Sequencing

 

In-depth analysis of cDNA sequences across the entire transcriptome or targeted genes

技术分享图片 Epigenetics

 

Detect DNA modifications in your samples while you sequence on the PacBio platform

技术分享图片 Targeted Sequencing

 

Study relevant genome targets across any regions of interest

Delivering highly accurate long reads to drive discovery in life science

原文:https://www.cnblogs.com/wangprince2017/p/13770438.html

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