只是简单的copy文件和添加快捷方式，安装和卸载时对程序是否运行进行检测
```nsi
;--------------------------------
;Include Modern UI
!include "MUI2.nsh"
;--------------------------------
;Interface Settings
!define MUI_ABORTWARNING
!define PRODUCTUNINSTKEY "Software/Microsoft/Windwos/CurrentVersion/Uninstall/AppName"
!define SOURCE_DIR "G:/emulator"
;--------------------------------
;General
;Name and file
Name "AppName"
OutFile "AppNameSetup.exe"
;Default installation folder
InstallDir "C:\AppName"
Icon "${SOURCE_DIR}/App.ico"
;UninstallIcon "App.ico"
UninstallCaption "uninstall AppName"
;Get installation folder from registry if available
InstallDirRegKey HKCU "Software\AppName" ""
;Request application privileges for Windows Vista
RequestExecutionLevel admin
;--------------------------------
;Pages
!define MUIICON "${SOURCEDIR}/App.ico"
!define MUIUNICON "${SOURCEDIR}/App.ico"
;!insertmacro MUIPAGELICENSE "${NSISDIR}\Docs\Modern UI\License.txt"
;!insertmacro MUIPAGECOMPONENTS
!insertmacro MUIPAGEDIRECTORY
!insertmacro MUIPAGEINSTFILES
!insertmacro MUIUNPAGEWELCOME
!insertmacro MUIUNPAGECONFIRM
!insertmacro MUIUNPAGEINSTFILES
!insertmacro MUIUNPAGEFINISH
;--------------------------------
;Languages
!insertmacro MUI_LANGUAGE "SimpChinese"
;--------------------------------
;Installer Sections
Function .onInit
;检测程序是否运行
FindProcDLL::FindProc "AppName.exe"
Pop $R0
IntCmp $R0 1 0 no_run
MessageBox MB_ICONSTOP "安装程序检测到 AppName 正在运行，请关闭之后再进行安装！"
Quit
no_run:
FunctionEnd
Section ""
SetOutPath "$INSTDIR"
;ADD YOUR OWN FILES HERE...
File /r "*"
Delete "AppName.nsi"
Delete "AppSetup.exe"
;Store installation folder
WriteRegStr HKCU "Software\AppName" "AppName" "$INSTDIR\AppName.exe"
;Create uninstaller
WriteUninstaller "$INSTDIR\Uninstall.exe"
CreateShortCut "$DESKTOP\AppName.lnk" "$INSTDIR\AppName.exe"
CreateShortCut "$SMPROGRAMS\AppName.lnk" "$INSTDIR\AppName.exe"
CreateShortCut "$SMPROGRAMS\uninstall AppName.lnk" "$INSTDIR\Uninstall.exe"
;CreateShortCut "$QUICKLAUNCH\AppName.lnk" "$INSTDIR\AppName.exe"
SectionEnd
Section -Post
WriteRegStr HKLM "Software\Microsoft\Windows\CurrentVersion\Uninstall\AppName" "DisplayIcon" "${SOURCE_DIR}/AppName.ico"
WriteRegStr HKLM "Software\Microsoft\Windows\CurrentVersion\Uninstall\AppName" "Publisher" "3g2win"
WriteRegStr HKLM "Software\Microsoft\Windows\CurrentVersion\Uninstall\AppName" "DisplayName" "AppName"
WriteRegStr HKLM "Software\Microsoft\Windows\CurrentVersion\Uninstall\AppName" "DisplayVersion " "1.0.0"
WriteRegStr HKLM "Software\Microsoft\Windows\CurrentVersion\Uninstall\AppName" "UninstallString" "$INSTDIR\Uninstall.exe"
SectionEnd
;--------------------------------
;Uninstaller Section
Function un.onInit
;检测程序是否运行
FindProcDLL::FindProc "AppName.exe"
Pop $R0
IntCmp $R0 1 0 no_run
MessageBox MB_ICONSTOP "卸载程序检测到 AppName正在运行，请关闭之后再卸载！"
Quit
no_run:
FunctionEnd
Section "Uninstall"
;ADD YOUR OWN FILES HERE...
Delete "$INSTDIR\Uninstall.exe"
RMDir /r "$INSTDIR"
Delete "$DESKTOP\AppName.lnk"
Delete "$SMPROGRAMS\AppName.lnk"
Delete "$SMPROGRAMS\uninstall AppName.lnk"
DeleteRegKey /ifempty HKCU "Software\AppName\AppName"
DeleteRegKey HKLM "Software\Microsoft\Windows\CurrentVersion\Uninstall\AppName"
;SetAutoClose true
SectionEnd
```
AppExample.nsi.rar http://files.cnblogs.com/grj1046/AppExample.nsi.rar
参考
NSIS：安装、卸载时检查程序是否正在运行 http://www.flighty.cn/html/bushu/20110402_115.html
NSIS 安装脚本（备忘）http://www.cnblogs.com/meteortent/archive/2013/06/10/3130770.html
[已解决] 卸载时注册表键无法删除，很奇怪 http://www.dreams8.com/thread-12800-1-1.html
原文：http://www.cnblogs.com/grj1046/p/3566516.html